Search results for "Quiescent state"

showing 3 items of 3 documents

Neuronal cell cycle: the neuron itself and its circumstances.

2015

Neurons are usually regarded as postmitotic cells that undergo apoptosis in response to cell cycle reactivation. Nevertheless, recent evidence indicates the existence of a defined developmental program that induces DNA replication in specific populations of neurons, which remain in a tetraploid state for the rest of their adult life. Similarly, de novo neuronal tetraploidization has also been described in the adult brain as an early hallmark of neurodegeneration. The aim of this review is to integrate these recent developments in the context of cell cycle regulation and apoptotic cell death in neurons. We conclude that a variety of mechanisms exists in neuronal cells for G1/S and G2/M check…

ApoptosisBrdU 5-bromo-2′-deoxyuridineReviewp75NTR neurotrophin receptor p75Nervous SystemG0 quiescent stateCKI Cdk-inhibitorNeuronsCell DeathNeurodegenerationCell CycleapoptosisNeurodegenerative DiseasesCell cycleCell biologymedicine.anatomical_structureInk inhibitor of kinaseBDNF brain-derived neurotrophic factorp38MAPK p38 mitogen-activated protein kinaseG2 growth phase 2Programmed cell deathS-phasePD Parkinson diseaseRb RetinoblastomaMcm2 minichromosome maintenance 2PCNA proliferating cell nuclear antigenMitosisContext (language use)BiologyCdk cyclin-dependent kinaseCNS central nervous systemS-phase synthesis phase.Cip/Kip cyclin inhibitor protein/kinase inhibitor proteinmedicineAnimalsHumansMolecular BiologyMitosisTetraploidAD Alzheimer diseasecell cycle re-entryDNA replicationCell BiologyNeuronmedicine.diseaseG1 growth phase 1neuronRGCs retinal ganglion cellsCell cycle re-entrytetraploidnervous systemApoptosisNeuronDevelopmental BiologyCell cycle (Georgetown, Tex.)
researchProduct

The Be/X-ray Transient V0332+53: Evidence for a tilt between the orbit and the equatorial plane?

1999

We present optical and infrared observations of BQ Cam, the optical counterpart to the Be/X-ray transient system V0332+53. BQ Cam is shown to be an O8-9Ve star, which places V0332+53 at a distance of ~7 kpc. H-alpha spectroscopy and infrared photometry are used to discuss the evolution of the circumstellar envelope. Due to the low inclination of the system, parameters are strongly constrained. We find strong evidence for a tilt of the orbital plane with respect to the circumstellar disc (pressumably on the equatorial plane). Even though the periastron distance is only ~ 10 R_*, during the present quiescent state the circumstellar disc does not extend to the distance of periastron passage. U…

PhysicsOrbital planeX-ray transientInfraredAstrophysics::High Energy Astrophysical PhenomenaAstrophysics (astro-ph)Quiescent stateFOS: Physical sciencesAstronomy and AstrophysicsAstrophysicsCircumstellar envelopeAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysicsAccretion (astrophysics)WavelengthSpace and Planetary ScienceAstrophysics::Solar and Stellar AstrophysicsAstrophysics::Earth and Planetary AstrophysicsSpectroscopyAstrophysics::Galaxy Astrophysics
researchProduct

From deterministic cellular automata to coupled map lattices

2016

A general mathematical method is presented for the systematic construction of coupled map lattices (CMLs) out of deterministic cellular automata (CAs). The entire CA rule space is addressed by means of a universal map for CAs that we have recently derived and that is not dependent on any freely adjustable parameters. The CMLs thus constructed are termed real-valued deterministic cellular automata (RDCA) and encompass all deterministic CAs in rule space in the asymptotic limit $\kappa \to 0$ of a continuous parameter $\kappa$. Thus, RDCAs generalize CAs in such a way that they constitute CMLs when $\kappa$ is finite and nonvanishing. In the limit $\kappa \to \infty$ all RDCAs are shown to ex…

Statistics and ProbabilityGeneral Physics and AstronomyFOS: Physical sciencesPattern Formation and Solitons (nlin.PS)Space (mathematics)01 natural sciences010305 fluids & plasmasLinear stability analysis0103 physical sciencesLimit (mathematics)Statistical physics010306 general physicsMathematical PhysicsBifurcationPhysicsCellular Automata and Lattice Gases (nlin.CG)Quiescent stateStatistical and Nonlinear PhysicsNonlinear Sciences - Chaotic DynamicsNonlinear Sciences - Pattern Formation and SolitonsCellular automatonNonlinear Sciences - Adaptation and Self-Organizing SystemsHomogeneousModeling and SimulationContinuous parameterChaotic Dynamics (nlin.CD)Adaptation and Self-Organizing Systems (nlin.AO)Nonlinear Sciences - Cellular Automata and Lattice Gases
researchProduct